Avoid chewing crunchy, hard, or sticky foods with the treated teeth for 2 weeks, as well as avoid touching treated areas. No floss or interproximal brushes are to be used at the treated site for 10 days after administration.

Patients should be advised that some mild to moderate sensitivity is expected after scaling and root planing and Arestin placement. If pain, swelling, or other problems occur please contact your doctor.